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MSH: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.,CSP: disorder characterized by reduction in the elements involved in blood coagulation due to their utilization in widespread blood clotting within the vessels; the activation of the clotting mechanism may arise from any of a number of disorders; in the late stages, it is marked by profuse hemorrhaging.,NCI: A disorder characterized by reduction in the elements involved in blood coagulation due to their utilization in widespread blood clotting within the vessels.,NCI: A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation fac
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