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MSH: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.,CSP: kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney; features include increased urine protein and declining kidney function.,MEDLINEPLUS: <p>If you have <a href='http://www.nlm.nih.gov/medlineplus/diabetes.html'>diabetes</a>, your blood sugar levels are too high. Over time, this can damage your kidneys. Your kidneys are filters that clean your blood. If they are damaged, waste and fluids build up in your blood instead of leaving your body.</p><p>Kidney damage from diabetes is called diabetic nephropathy. It begins long before you have symptoms. An early sign of it is small a
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