| umls-concept:C0011334 | skos:definition | MSH: Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification.,CSP: localized destruction of calcified tissue initiated on the tooth surface by decalcification of the enamel of the teeth, followed by enzymatic lysis of organic structures, leading to cavity formation that, if left untreated penetrates the enamel and dentin and may reach the pulp.,NCI: The decay of a tooth, in which it becomes softened, discolored, and/or porous.,NCI: A disorder characterized by the decay of a tooth, in which it becomes softened, discolored and/or porous. | lld:umls |
