umls-concept:C0007407 | skos:definition | MSH: Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine. EC 2.1.1.6.,NCI: the catechol-O-methyltransferase (COMT) pathway is essential for preventing the generation of estrogen derived reactive oxygen species. (from Thorax 2000;55:574-578) | lld:umls |