| umls-concept:C0006514 | skos:definition | MSH: A substituted carcinogenic nitrosamine.,NCI: A substance that is used in cancer research to cause bladder tumors in laboratory animals. This is done to test new diets, drugs, and procedures for use in cancer prevention and treatment.,NCI: A synthetic carcinogenic compound found in a variety of smokes and industrial products, N-butyl-N-4-hydroxybutyl nitrosamine is used in biomedical research to induce transitional and squamous cell urinary bladder cancers and to promote experimental hepatocarcinogenesis, probably through abnormal DNA methylation. (NCI04) | lld:umls |
