Lincosamide Antibiotic

Source:http://linkedlifedata.com/resource/umls/id/C2826567

NCI: Any agent belonging to the class of lincosamide antibiotics with antibacterial activity. Lincosamide antibiotics bind to the 23s portion of the 50S subunit of bacterial ribosomes. This prevents translocation of the peptidyl-tRNA from the A-site to the P-site during protein synthesis. This results in the release of an incomplete protein and disrupts protein synthesis.

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