| umls-concept:C1708019 | skos:definition | NCI: Human FGR wild-type allele is located within 1p36.2-p36.1 and is approximately 23 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase FGR protein, is involved in the regulation of outside-in signaling-dependent sustained neutrophil adhesion. Amplification of this gene is associated with the development of hormone-resistant prostate cancer. | lld:umls |
