Source:http://linkedlifedata.com/resource/umls/id/C1707128
NCI: Human CHEK1 wild-type allele is located within 11q24-q24 and is approximately 29 kb in length. This allele, which encodes serine/threonine-protein kinase Chk1 protein, plays a role in the induction of cell cycle arrest at the G2/M checkpoint in response to either DNA damage or the presence of unreplicated DNA.