EEF1A2 protein, human

Source:http://linkedlifedata.com/resource/umls/id/C1531428

NCI: Expressed in terminally differentiated brain, heart, and skeletal muscle cells by human EEF1A2 Gene (EF-Tu/EF-1A Family), 463-aa 50-kDa Elongation Factor 1A2 is an alpha subunit of elongation factor-1 (EEF1) complex responsible for enzymatic delivery and GTP-dependent binding of aminoacyl tRNAs to the A-site of ribosomes during protein biosynthesis. EEF1A gene coding regions are highly similar; EEF1A2 exhibits 92% amino acid identity to EEF1A1. EEF1A2 has oncogenic properties: it enhances focus formation, allows anchorage-independent growth, and decreases fibroblast doubling time. EEF1A2 may be critical in development of ovarian cancer. (NCI)

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