WF, Rat Strain

Source:http://linkedlifedata.com/resource/umls/id/C1520110

NCI: A Wistar substrain derived by Furth (1945), this inbred rat strain is a white albino with pink eyes, genotype c. The Wistar Furth rat carries a heteropyenotic Y chromosome that is used as a cellular marker.,NCI: A Wistar substrain derived by Furth (1945), this inbred rat strain is a white albino with pink eyes, genotype c. The Wistar Furth rat carries a heteropyenotic Y chromosome that is used as a cellular marker. Leukemia develops in 15-22% of these rats, which is characterized by mononuclear cells with reddish granules. The Wistar Furth rat exhibits good reproductive performance and is docile, with an averages life span of 22 months.,NCI: In females tumors include 27% pituitary, 21% mammary, 3% adrenal, 9% leukemia (generalized), 7% lymphoma (malignant), 3% lipomas and 4% unclassified (Kim et al 1960). Mean life span 21 months in females and 23 months in males. Leukemia 15-22% characterised by an unusual type of mononuclear cell containing reddish granules. Incidence of spontaneous pituitary tumors 38

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