Ornithine Decarboxylase Inhibitor

Source:http://linkedlifedata.com/resource/umls/id/C1518618

NCI: Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.

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