IFN Alpha Signaling Pathway

Source:http://linkedlifedata.com/resource/umls/id/C1512582

NCI: Interferon alpha plays a role in viral infections. Signaling takes place through an IFN receptor complex consisting of two alpha chains (type I receptor) complexed with Jak1 and Tyk2. These kinases phosphorylate Stat1 and Stat2 respectively.

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