Death Domain

Source:http://linkedlifedata.com/resource/umls/id/C1511738

NCI: The death domain is a protein region, approximately 80 amino acids long, that is required for transmission of the cytotoxic signal of apoptosis and is present in the TNF receptor, FAS, and several downstream signaling molecules. Transmission of the apoptotic signal requires the functional interaction of proteins via the death domain.

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