Source:http://linkedlifedata.com/resource/umls/id/C1451270
CSP: active principle in the buccal gland secretion (saliva) of leeches; it acts as an antithrombin and as an antithrombotic agent.,MSH: Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.