Source:http://linkedlifedata.com/resource/umls/id/C1434639
NCI: Dual specificity mitogen-activated protein kinase kinase 4 (399 aa, ~44 kDa) is encoded by the human MAP2K4 gene. This protein is involved in the modulation of MAPK signaling pathways.,NCI: mitogen-activated protein (MAP) kinase kinase 1 (MAPKK-1 or MEK-1). A regulator of the Ras intracellular signaling pathway. (from Yu et al. Curr Biol 1998 8:56-64),NCI: A component of the RAS intracellular signaling pathway, MAP2K1 is a critical activating protein kinase of MAP kinase. p53 activates NFKB through a RAF/MAP2K1/p90(RSK) pathway. (from Yu et al. Curr Biol 1998. 8:56, OMIM 176872, and NCI)