Source:http://linkedlifedata.com/resource/umls/id/C1366903
NCI: A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 3 exons of the PML gene with the last 7 exons of the RARA gene. This fusion is associated with acute promyelocytic leukemia. Three transcript variants are possible based on the three breakpoint clusters in the PML gene.,NCI: This gene plays a role in tumor suppression and is involved in the regulation of p53 in response to oncogenic signal transduction.