Source:http://linkedlifedata.com/resource/umls/id/C1333201
MSH: A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.,NCI: Cytosolic phospholipase A2 is involved in cell cycle progression via regulation of arachidonic acid metabolism. (Cell Mol Life Sci 2002;59:181-8),NCI: Exhibiting sequence similarity and distinct tissue distributions, calcium-dependent (C2 domain) or -independent human Cytosolic Phospholipases A2 (Group IV) hydrolyze membrane phospholipids (sn-1 or sn-2 bonds) in phospholipid remodeling or in releasing a 20-carbon arachidonic acid precursor from membrane phospholipids for many eicosanoid mediators of inflammatory responses and other cellular processes, including prostaglandins, thromboxanes, and leukotrienes. (NCI)