siplizumab

Source:http://linkedlifedata.com/resource/umls/id/C1328709

NCI: A monoclonal antibody that is being studied in the treatment of certain lymphoproliferative disorders and psoriasis.,PDQ: A monoclonal immunoglobulin G1 antibody with potential antineoplastic activity. Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby triggering a host immune response that results in lysis of CD2+ cells, selective suppression of the immune system, and control of activated T cell growth. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=346499&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=346499&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38685" NCI Thesaurus),NCI: A humanized monoclonal immunoglobulin G1 antibody with potential antineoplastic activity. Siplizumab binds to CD2, a specific receptor found in T cells and NK cells, thereby triggering a host immune response that results in

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