Source:http://linkedlifedata.com/resource/umls/id/C1175067
NCI: A substance that is being studied as a treatment for advanced prostate cancer and for pain caused by prostate cancer that has spread to the bone. It belongs to the family of drugs called endothelin ETA receptor antagonists.,PDQ: An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progression, angiogenesis, and metastasis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=270682&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=270682&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26678" NCI Thesaurus),NCI: An orally active synthetic substituted phenylethenesulfonamide. As a selective endothelin A receptor antagonist, YM598 inhibits endothelin-mediated mechanisms involved in tumor cell growth and progres