Source:http://linkedlifedata.com/resource/umls/id/C1166833
GO: A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex. [PMID:15117830, PMID:16710609],MSH: Complexes composed of subunits of the different sarcoglycans. The sarcoglycan complex is a component of the DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX. Mutations abolishing the expression of sarcoglycans of the muscle sarcoglycan complex are associated with of LIMB-GIRDLE MUSCULAR DYSTROPHY.