| umls-concept:C1160083 | skos:definition | GO: The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. [GOC:dph, ISBN:0878932437],MSH: An early embryonic developmental process of CHORDATES that is characterized by morphogenic movements of ECTODERM resulting in the formation of the NEURAL PLATE; the NEURAL CREST; and the NEURAL TUBE. Improper closure of the NEURAL GROOVE results in congenital NEURAL TUBE DEFECTS. | lld:umls |
