Source:http://linkedlifedata.com/resource/umls/id/C0872078
MSH: Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.,CSP: membrane protein associated with early onset familial Alzheimer's disease.