Source:http://linkedlifedata.com/resource/umls/id/C0812217
NCI: Mutated forms of G-protein genes which encode a diverse group of regulatory proteins that act as molecular switches. Under normal cellular conditions, the activity of these proteins is tightly controlled. Activation of G-protein proto-oncogenes via mutation results in G-protein oncogenes. These aberrant genes express protein products that disrupt normal cell function.