Source:http://linkedlifedata.com/resource/umls/id/C0673406
NCI: G Protein-Coupled Receptor Kinase 7, encoded by the GPRK7 gene, belongs to the GPRK subfamily of the Ser/Thr family of protein kinases. This membrane-bound protein phosphorylates cone opsins, thereby initiating their deactivation in color vision. (from Swiss-Prot),NCI: Expressed in retina by human GPRK7 Gene (GPRK family), membrane-bound 553-aa 62-kDa G Protein-Coupled Receptor Kinase 7 is a Ser/Thr kinase containing an RGS domain, a C-terminal CaaX motif for isoprenylation and carboxymethylation, an autophosphorylation site (Ser491), and a geranylgeranylation motif. GRK7 catalyzes rhodopsin phosphorylation, initiating their deactivation in a light-dependent manner. (NCI)