Source:http://linkedlifedata.com/resource/umls/id/C0524724
NCI: A fastening device consisting of a bent wire designed to pierce and hold.,UMD: Small pieces of thin metallic wires, typically U-shaped, that are appropriate for mechanically fastening tissues together. Most staples are made of stainless, non-absorbable, biocompatible metals (e.g., stainless steel, chromium, titanium) or metallic alloys; they are available in several different shapes and calibers according to the intended use (e.g., bone, vessel, skin). Staples are used in surgery to join many types of organs and tissues, especially in the anastomosis of tubular structures such as the gastrointestinal tract and vasculature; other staples are used for skin wound closure. Most staples are delivered using dedicated instruments (e.g., staplers, drivers). Stapling is generally faster and produces less tissue trauma than standard suturing techniques.