gp96 heat shock protein-peptide complex

Source:http://linkedlifedata.com/resource/umls/id/C0393074

NCI: An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation. (NCI04),NCI: A vaccine made from a patient's tumor cells that may help the body's immune system kill cancer cells. This vaccine is used to treat kidney cancer, a type of brain cancer called glioma, and metastatic melanoma (a type of skin cancer that has spread). It is also being studied in the treatment of other types of cancer.,PDQ: An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42682&idtype=1" active clinical trials or "http://www.canc

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