CCAAT/Enhancer Binding Protein Alpha

Source:http://linkedlifedata.com/resource/umls/id/C0378310

NCI: CCAAT/enhancer binding protein alpha (358 aa, ~38 kD) is encoded by the human CEBPA gene. This nuclear protein is a DNA-binding bZIP transcription factor that, as a homodimer, recognizes common motifs in both the promoter (CCAAT sequence) and enhancer (core homology sequence) regions of genes.,MSH: A CCAAT-enhancer-binding protein found in LIVER; ADIPOSE TISSUE; INTESTINES; LUNG; ADRENAL GLANDS; PLACENTA; OVARY and peripheral blood mononuclear cells (LEUKOCYTES, MONONUCLEAR). Experiments with knock-out mice have demonstrated that CCAAT-enhancer binding protein-alpha is essential for the functioning and differentiation of HEPATOCYTES and ADIPOCYTES.

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