interferon alpha-beta receptor

Source:http://linkedlifedata.com/resource/umls/id/C0254653

MSH: A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.,NCI: IFN alpha-beta receptor beta chain (515 aa, 58 kD) is a cell communication process protein that is encoded by the human IFNAR1 gene and has a role in signal transduction.

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