Source:http://linkedlifedata.com/resource/umls/id/C0249042
NCI: Human integrin beta-5 protein (799 aa, ~88 kD) is encoded by the integrin, beta 5 gene (ITGB5). This type I membrane protein forms a heterodimer with integrin alpha-V protein. The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration.