Source:http://linkedlifedata.com/resource/umls/id/C0246486
MSH: A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.,NCI: Expressed in skeletal muscle, brain, heart, placenta, lung, liver, pancreas, kidney, and fibroblasts by human MAPK6 Gene (MAPK Family), 721-aa 83-kDa nuclear MAP Kinase 6 is a Ser/Thr protein kinase activated by protein phosphorylation cascades that acts as an integration point for multiple biochemical signals and likely promotes entry in the cell cycle. MAPK6 phosphorylates MAP2. (NCI)