protein-tyrosine kinase p55(blk)

Source:http://linkedlifedata.com/resource/umls/id/C0218989

NCI: Encoded by the BLK gene, p55-BLK is a non-receptor protein tyrosine kinase member of the SRC protooncogene family and, on the basis of its preferential expression in B-lymphoid cells, it may function in a signal transductory pathway specific to this lineage. Expression of BLK in immature T-cells suggests that it may play an important role in thymopoiesis. The protein has SH3, SH2, and catalytic domains that contain SRC tyrosine kinase family consensus sequences. (from OMIM 191305 and NCI),NCI: A protein tyrosine kinase activated within seconds after crosslinking the mIg complex on B cells.

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