Chemokine (C-C Motif) Ligand 4

Source:http://linkedlifedata.com/resource/umls/id/C0209338

MSH: A CC chemokine with specificity for CCR5 RECEPTORS. It is a chemoattractant for NK CELLS; MONOCYTES and a variety of other immune cells. This chemokine is encoded by multiple genes.,NCI: MIP-1 beta chemokine is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating hematopoiesis. MIP-1 beta is induced rapidly after T-cell activation with phytohemagglutinin, B-cell activation with Staphylococcus aureus, and monocyte activation with lipopolysaccharide. It is predominantly synthesized by perforin-low memory CD8+ T-cells, a major non-cytotoxic population of CD8+ T-cells. (from OMIM 182284 and NCI),NCI: The recombinant form of endogenous MIP-1 beta chemokine that chemoattracts both neutrophils and monocytes, stimulates macrophages, and stimulates myelopoietic cell growth.

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