Source:http://linkedlifedata.com/resource/umls/id/C0207628
NCI: An antiviral drug that is being studied as a treatment for herpesvirus. It belongs to the family of drugs called nucleic acid synthesis inhibitors.,NCI: A synthetic thymidine analogue with potent antiviral activity against herpes simplex and varicella zoster viruses. Sorivudine is phosphorylated into triphosphate form within the cells; this metabolite interferes with viral DNA replication by inhibiting DNA polymerase activity without been incorporated into elongating viral DNA. Due to the dangerous effects of drug-drug interactions via its metabolite, sorivudine has been removed from the market.