| umls-concept:C0206120 | skos:definition | MSH: Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.,CSP: diminished immune responsiveness to specific antigens; induced or programmed clonal lymphocyte anergy is believed to be the second major mechanism (after clonal deletion) of the development of self tolerance by the immune system.,NCI: Diminished immune responsiveness to specific antigens. Induced or programmed clonal lymphocyte anergy is believed to be the second major mechanism (after clonal deletion) of the development of self tolerance by the immune system. | lld:umls |
