umls-concept:C0167636 | skos:definition | NCI: Paired box protein Pax-5 (391 aa, ~42 kDa) is encoded by the human PAX5 gene. This protein plays a role in B-cell differentiation, neural development, spermatogenesis and gene transcription.,MSH: A transcription factor that is essential for CELL DIFFERENTIATION of B-LYMPHOCYTES. It functions both as a transcriptional activator and repressor to mediate B-cell commitment. | lld:umls |