Atovaquone

Source:http://linkedlifedata.com/resource/umls/id/C0165603

CSP: broad-spectrum antiparasitic drug found to be active against Pneumocystis carinii pneumonia in AIDS patients.,MSH: A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.,NCI: A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.

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