Source:http://linkedlifedata.com/resource/umls/id/C0142825
NCI: The sodium salt of citrate with alkalinizing activity. Upon absorption, sodium citrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis. In addition, increases in free sodium load due to sodium citrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect.,PDQ: The sodium salt form of citrate with alkalinizing property. Upon absorption, sodium citrate dissociate and causes increased plasma bicarbonate concentration, thereby buffer excess H+, raise blood pH and reverse the clinical manifestations of acidosis. Furthermore, increased free sodium load could foster intravascular blood volume, and facilitate excretion of bicarbonate compounds and result in anti-urolithic effect. Check for "http://www.c