Source:http://linkedlifedata.com/resource/umls/id/C0120465
CSP: proteins which catalyze GDP/GTP exchange.,MSH: Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.,NCI: GEFs. Proteins that catalyze the release and exchange of GDP for GTP from GTP-binding regulatory proteins, which are active in the GTP-bound form. The prototypical GEF is the eukaryotic initiation factor 2b, eIF-2B. Among other GTP-binding proteins regulated in this manner is p21 ras.