Source:http://linkedlifedata.com/resource/umls/id/C0105421
NCI: The 160 kD BCR phosphoprotein exhibits a unique serine/threonine kinase activity, at least two SH2 binding sites, and a C-terminal GTPase activating domain for p21(rac). The Philadelphia translocation produces a BCR-ABL1 chimeric product required for induction and maintenance of leukemia. (from OMIM 151410 and NCI)