Adenovirus E1B Proteins

Source:http://linkedlifedata.com/resource/umls/id/C0101584

MSH: Proteins transcribed from the E1B region of ADENOVIRUSES which are involved in regulation of the levels of early and late viral gene expression.,NCI: Human E1B protein (175 aa, 20 kDa) protein is encoded by the human adenovirus 2 (HadV-2) gene. This protein is transcribed by the E1B region of the HadV-2 gene, which is involved in the regulation of E1B protein levels. This protein is an inhibitor of apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis. Without E1B function, virus production is compromised due to the premature death of the host cell.

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