IFN-Stimulated Gene Factor 3 Complex

Source:http://linkedlifedata.com/resource/umls/id/C0083029

MSH: A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.

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