| umls-concept:C0082529 | rdf:type | umls-semnetwork:T116 | lld:umls |
| umls-concept:C0082529 | rdf:type | umls-semnetwork:T126 | lld:umls |
| umls-concept:C0082529 | rdf:type | skos:Concept | lld:umls |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:ANAT | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:GENE | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:PHYS | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:PHEN | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:PROC | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:CONC | lld:calbc |
| umls-concept:C0082529 | calbc:hasCorrelation | calbc-group:CHEM | lld:calbc |
| umls-concept:C0082529 | skos:exactMatch | pubmed-mesh:Mitogen-Activat... | lld:mappings |
| umls-concept:C0082529 | skos:definition | MSH: A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.,NCI: Mitogen-activated protein kinases (MAPKs) are serine-threonine protein kinases activated in response to a variety of extracellular stimuli and encoded by a multigene family. The MAPKs are part of complex protein kinase cascades. One class of MAPKs includes (among other ERKs) the extracellular signal-regulated kinases ERK1 (p44MAPK) and ERK2 (p42MAPK), activated by the RAF/MEK/ERK signaling pathway. ERK1/2 are widely involved in eukaryotic signal transduction. Upon activation, ERKs translocate to the nucleus and phosphorylate nuclear targets. Phosphorylated ERKs form essential dimers with phosphorylated and unphosphorylated ERK partners. Dimerization is part of the mechanism of MAP kinase family action. Mitogen-activated protein kinases (MAP | lld:umls |
| umls-concept:C0082529 | skos:inScheme | lld:umls | lld:umls |
| umls-concept:C0082529 | skos:narrower | umls-concept:C0527339 | lld:umls |
| umls-concept:C0082529 | skos-xl:prefLabel | umls-label:A7101934 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18025710 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6959668 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7608773 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6972831 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17905902 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7595039 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6959644 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6967601 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17954038 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6976133 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18669640 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18049983 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6972626 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17978340 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6955454 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6988041 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7629965 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A1302273 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18613990 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17954039 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6988040 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7588506 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17881755 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6972793 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6972787 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6993741 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7604169 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7604246 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A7629964 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18025707 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6971943 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6971942 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17905900 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6967206 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A6970975 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A17905905 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18651162 | lld:umls |
| umls-concept:C0082529 | skos-xl:altLabel | umls-label:A18632502 | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
| umls-concept:C0082529 | umls:relation | http://linkedlifedata.com/r... | lld:umls |
