Source:http://linkedlifedata.com/resource/umls/id/C0079122
MSH: A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome.,CSP: sequential isolation of clones carrying overlapping sequences of DNA, allowing large regions of the chromosome to be spanned; often performed to reach a particular locus of interest.