Source:http://linkedlifedata.com/resource/umls/id/C0072470
NCI: A protein on the surface of some cells that binds to biologic substance called stem cell factor (SCF). SCF causes certain types of blood cells to grow. The stem cell factor receptor is found at high levels or in a changed form on some types of cancer cells. This may cause these cells to grow rapidly when SCF is present. The stem cell factor receptor is a type of receptor tyrosine kinase.,NCI: Cell surface receptor for Stem Cell Factor. Product of the KIT gene.,NCI: Encodes mast cell growth factor, a tyrosine protein kinase. Also known as SCF Receptor and CD117. Can be activated to become an oncogene. (See Oncogene, KIT),MSH: A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated wit