| umls-concept:C0058594 | skos:definition | CSP: nonEC; enzyme which synthesizes a short RNA primer to initiate DNA- directed DNA biosynthesis.,MSH: A single-stranded DNA-dependent RNA polymerase that functions to initiate, or prime, DNA synthesis by synthesizing oligoribonucleotide primers. EC 2.7.7.-.,NCI: Heterodimeric human DNA Primase consists of a 49-kDa (small) and a 58-kDa (large) subunit. Eukaryotic DNA replication involves a replication apparatus containing the key enzymatic components DNA Primase and DNA Polymerase Alpha. DNA Primase is a polymerase that synthesizes small RNA primers for Okazaki fragments made during discontinuous DNA replication. (NCI) | lld:umls |
