Source:http://linkedlifedata.com/resource/umls/id/C0058099
NCI: A flavoprotein (FAD, FMN). Catalyzes the reaction of S-dihydroorotate and oxygen into orotate and hydrogen peroxide. Ferricyanide can act as acceptor. [EC 1.3.3.1 created 1961] (from IUBMB),NCI: A drug target in the pyrimidine biosynthetic pathway. Variation in gene expression or sequence may alter the efficacy of chemotherapy.