Calgranulin A

Source:http://linkedlifedata.com/resource/umls/id/C0054504

NCI: A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of cancer. It is being studied as a biomarker for breast cancer.,MSH: A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.,NCI: Constitutively expressed in epithelial cells and in macrophages during chronic inflammation by human S100A8 Gene (S100 Family), 93-aa 11-kDa homodim

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