| umls-concept:C0044602 | skos:definition | MSH: A phosphatidylinositol 3-kinase that catalyzes the conversion of 1-phosphatidylinositol into 1-phosphatidylinositol 3-phosphate.,NCI: A type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have higher-than-normal levels of phosphatidylinositol-3 kinase.,NCI: An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink) | lld:umls |
