Source:http://linkedlifedata.com/resource/umls/id/C0041484
MSH: An enzyme of the oxidoreductase class that catalyzes the reaction between L-tyrosine, L-dopa, and oxygen to yield L-dopa, dopaquinone, and water. It is a copper protein that acts also on catechols, catalyzing some of the same reactions as CATECHOL OXIDASE. EC 1.14.18.1.,NCI: A group of copper proteins that also catalyze the reaction of EC 1.10.3.1 catechol oxidase, if only 1,2-benzenediols are available as substrate. (from IUBMB),NCI: Expression increased after UV-B radiation and encoded as 2 alternative isoforms by human TYR Gene (Tyrosinase Family), 548-aa 63-kDa Tyrosinase is a type I melanosomal membrane protein and rate-limiting copper-binding oxidase containing glycosylation and histidine-rich sites that catalyzes the first 2 steps, and a subsequent step(s), in tyrosine to DOPA to DOPA-quinone conversion to melanin and formation other polyphenolic compounds. TYR defects cause OCA-IA and OCA-IB. (NCI)