Tubercidin

Source:http://linkedlifedata.com/resource/umls/id/C0041286

MSH: An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.,CSP: antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids; an antineoplastic antimetabolite.,PDQ: An antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity. Tubercidin is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39728&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39728&idtype=1&closed=1" closed clinical trials using this agent. ("http://ncit

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